If you suffered from heart failure or other serious medical conditions after taking Onglyza or Kombiglyze XR Lawsuit, you may be eligible to file a lawsuit. If you are considering filing a lawsuit against AstraZeneca, you should contact an experienced pharmaceutical liability lawyer.
The FDA recently issued a warning that two newer diabetes medications – Onglyza and Kombiglyze XR – increase the risk of heart failure. These drugs are marketed by AstraZeneca and Bristol-Myers Squibb, respectively.
Saxagliptin is a type of incretin-based medication
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Saxagliptin is a type of incretin-based medication used with diet and exercise to help lower blood sugar levels in patients with Type 2 diabetes. It is part of a group of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors.
In clinical trials, people who took saxagliptin had less weight gain and had better glucose control than those who took metformin alone. They also had fewer aches and pains, less depression, and were less likely to have heart attack or stroke.
Some people who take saxagliptin have a higher risk of developing inflammation of the pancreas (pancreatitis) and other serious side effects. This is more likely if you have certain medical problems, like cancer or kidney disease.
Kombiglyze XR is a combination medication that contains the anti-diabetic medications saxagliptin and metformin. It is taken by mouth, usually once a day with or without food. It is not recommended for use during pregnancy or while breast-feeding.
It is used to treat Type 2 diabetes
Kombiglyze XR is a type of medication that is used to treat Type 2 diabetes. It works by increasing the amount of insulin the body makes after meals. It also reduces the amount of sugar that is absorbed in the intestine.
It is used with a diet plan and exercise to help people control their blood sugar levels. Patients should follow their doctor’s instructions closely and take their medicine as directed.
KOMBIGLYZE XR is not recommended in pregnant women or in patients who may become pregnant while taking it. It is safe to use in breastfeeding women, but it can cause lactic acidosis if the mother drinks too much alcohol while on the medication.
Lactic acidosis can be dangerous, so it is important to keep the patient in contact with their healthcare provider if they have any signs or symptoms of it. The condition can lead to respiratory distress, abdominal pain and weakness.
KOMBIGLYZE XR should not be used by people who have kidney problems, because it can cause them to get a lot of lactic acid in the blood. It is not good for people who have a heart condition, as it can cause them to have low blood pressure.
It is manufactured by AstraZeneca
AstraZeneca is the manufacturer of Onglyza and Kombiglyze XR. These medications work by boosting the amount of insulin your body produces after meals. They also lower blood sugar levels in your body by inhibiting an enzyme called dipeptidyl peptidase-4 (DPP-4).
People with type 2 diabetes can use these drugs to control their blood sugar. They must also follow a healthy diet and exercise regularly.
The medicine also has a black box warning, which means it may cause a rare condition called lactic acidosis. This can cause respiratory distress and abdominal pain.
However, it is rare for this to happen in people who take the drug. If you experience any of these symptoms, contact your doctor immediately.
Other medicines can affect how Onglyza and Kombiglyze work, including some antifungal drugs, certain types of cancer medications, certain antibiotics and other medicines that can increase your risk for lactic acidosis. Patients should tell their doctors about all the medications they take.
It is sold in the United States
Kombiglyze XR is a medicine that contains saxagliptin and metformin. It is used to treat Type 2 diabetes. It can also help reduce the risk of heart failure.
The medication works by increasing the amount of insulin your body produces after meals. It also decreases the amount of sugar that is absorbed from your stomach.
It is available in tablet form, which is usually taken once a day. The tablets come in different dosage strengths, including 2.5 mg and 5 mg.
Patients should take the medication by mouth without crushing or chewing it. If you have trouble swallowing, talk to your doctor.
This drug may cause serious side effects, such as lactic acidosis (a build-up of an acid called lactate in the blood). You should get medical help right away if you have signs of this problem, such as feeling cold or having a slow heart rate or weak muscles.
You should also not drink alcohol while taking this medication. Alcohol can make it harder to control your blood sugar and increase your risk of lactic acidosis.